THE 2-MINUTE RULE FOR PHENOBARBITAL HALF GRAIN

Kramp 1978 This can be the only readily available potential RCT that compares barbiturate to benzodiazepine for patients with serious alcohol withdrawal. 91 patients were randomized to obtain intramuscular diazepam vs. oral barbital (an early long-acting barbiturate). To protect blinding of doctors and patients, all patients ended up treated simult